Similarly, clinicians long have noted significant kidney enlargement (i.e., nephromegaly) in direct proportion to liver enlargement among chronic alcoholic2 patients afflicted with liver cirrhosis. Laube and colleagues (1967) suggested that both cellular enlargement and cell proliferation contribute to such nephromegaly. The kidneys continuously perform their tasks of purifying and balancing the constituents of the body’s fluids. Although resilient, the kidneys can deteriorate as a result of malnutrition, alcohol abuse or dependence, or liver and other diseases. Healthy kidneys are vital to the function of all the body’s organs and systems.
That’s why it’s important to attend all your checkups and work with your healthcare provider on a treatment plan. Early detection and appropriate treatment are important in slowing the disease progression, with the goal of preventing or delaying kidney failure. You’ll need to keep your medical appointments, take your medications as prescribed, stick to a nutritious diet and monitor your blood pressure and blood sugar.
But treatment can prevent complications and also improve everyday life for patients with type 1 diabetes. And the more we learn and develop treatment for the disorder, the better the outcome. Chronic kidney disease (CKD and chronic renal disease) means that there’s damage to your kidneys and they aren’t working as well as they should.
Established liver disease impairs this important balancing act, however, by either greatly augmenting or reducing the rates of plasma flow and filtration through the glomerulus. One reason alcohol may affect the kidneys is through acute kidney injury. This may result from high levels of toxins leading to tissue injury and inflammation. Kidneys that have been overworked due to excess alcohol consumption don’t function properly. This makes them less able to filter blood and maintain the correct water balance in the body. The hormones that control kidney function can also be adversely affected.
While many kidney patients have concerns about not keeping on weight, adding alcohol is not a solution to prevent wight loss. In general, alcohol does not have high amounts of potassium. Wine and beer are typically low in potassium (less than alcohol and kidneys 200 milligrams per serving). Please check with a medical professional if you need a diagnosis and/or for treatments as well as information regarding your specific condition. In case of emergency, call or go to the nearest emergency department.
Kidney pain after drinking alcohol may occur due to acute kidney injury or an infection. Moderate drinking should not cause kidney pain, but binge drinking or frequent drinking may cause kidney problems. Heavy drinking can also cause liver disease, which makes your kidneys have to work harder. When you have liver disease, your body doesn’t balance the flow and filtering of blood as well as it should. This has a harmful effect on your overall health and can increase the chance of complications.
There are several possible protective mechanisms of alcohol on kidney function. Ethanol and polyphenol both have anti-oxidative effects and ethanol improves polyphenol absorption, thereby contributing to bioavailability [4,5,6]. Furthermore, alcohol has an anti-inflammatory effect, with increased serum interleukin-10 levels and decreased serum interleukin-16 levels [20].
If an acute alcoholic binge induces extensive vomiting, potentially severe alkalosis may result from losses of fluid, salt, and stomach acid. Alcohol can induce abnormally high phosphate levels (i.e., hyperphosphatemia) as well as abnormally low levels. In fact, hyperphosphatemia often precedes hypophosphatemia. Alcohol consumption apparently leads to excessive phosphate levels by altering muscle cell integrity and causing the muscle cells to release phosphate.
Under these conditions, the urine formed is dilute and electrolyte concentration in the blood simultaneously rises. Another study with dogs (Beard et al. 1965) disclosed that the effects of chronic alcohol consumption endured even longer. The investigators noted increased plasma and extracellular fluid volume 1 week after chronic alcohol ingestion, and these volume expansions persisted for the remaining 7 weeks of the study. Similar alterations have been found in body fluid volumes among chronic alcoholic patients. One way in which alcohol directly affects the kidneys is by altering the form and structure of this pair of organs, as demonstrated by various animal studies.